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Nanoscience goes 'big': Discovery could lead to enhanced electronics


One of the main applications of this research that Cha and her group are interested in is for sensing. "There is no foreseeable route to be able to build a complex array of different nanoscale sensing elements currently," said Cha, a former IBM research scientist who joined the UCSD Jacobs School of Engineering faculty in 2008. "Our work is one of the first clear examples of how you can merge top down lithography with bottom up self assembly to build such an array. That means that you have a substrate that is patterned by conventional lithography, and then you need to take that pattern and merge it with something that can direct the assembly of even smaller objects, such as those having dimensions between 2 and 20 nanometers. You need an intermediate template, which is the DNA origami, which has the ability to bind to something else much smaller and direct their assembly into the desired configuration. This means we can potentially build transistors from carbon nanotubes and also possibly use nanostructures to detect certain proteins in solutions. Scientists have been talking about patterning different sets of proteins on a substrate and now we have the ability to do that."
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