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Discussion of the Essence# programming language, and related issues and technologies. |
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From Physorg.com:
A team of scientists from Columbia University, Arizona State University, the University of Michigan, and the California Institute of Technology (Caltech) have programmed an autonomous molecular "robot" made out of DNA to start, move, turn, and stop while following a DNA track.Full article
From Pysorg.com:
In a single day, a solitary grad student at a lab bench can produce more simple logic circuits than the world's entire output of silicon chips in a month.Full article
From PhysOrg.com:
An Arizona State University graduate student, Jinglin Fu, in collaboration with Biodesign Institute researchers Neal Woodbury and Stephen Albert Johnston, has pioneered a technique that improves on scientists' ability to harness and modulate enzyme activity.Full article
From PhysOrg.com:
Scientists with Berkeley Lab's Molecular Foundry have developed a nanowire-based imaging technique by which atomic force microscopy could be used to study biological cells and other soft materials in their natural, liquid environment without tearing apart or deforming the samples. This could provide scientists with the long coveted non-destructive means of dynamically probing soft matter.Full article
From PhysOrg.com:
A team of MIT researchers has found a novel way to mimic the process by which plants use the power of sunlight to split water and make chemical fuel to power their growth. In this case, the team used a modified virus as a kind of biological scaffold that can assemble the nanoscale components needed to split a water molecule into hydrogen and oxygen atoms.Full article
From PhysOrg.com:
Researchers in Singapore are reporting this week that they have gleaned key insights into the architecture of a protein that controls iron levels in almost all organisms. Their study culminated in one of the first successful attempts to take apart a complex biological nanostructure and isolate the rules that govern its natural formation.Full article
From PhysOrg.com:
Like a magician who says, "Pick a card, any card," Stanford University computer scientist Debashis Sahoo, PhD, seemed to be offering some kind of trick when he asked researchers at the Stanford Institute for Stem Cell Biology and Regenerative Medicine to pick any two genes already known to be involved in stem cell development. Finding such genes can take years and hundreds of thousands of dollars, but Sahoo was promising the skeptical stem cell scientists that, in a fraction of a second and for practically zero cost, he could find new genes involved in the same developmental pathway as the two genes provided.Full article
From PhysOrg.com:
In a leap toward making stem cell therapy widely available, researchers at the Ansary Stem Cell Institute at Weill Cornell Medical College have discovered that endothelial cells, the most basic building blocks of the vascular system, produce growth factors that can grow copious amounts of adult stem cells and their progeny over the course of weeks. Until now, adult stem cell cultures would die within four or five days despite best efforts to grow them.Full article
From PhysOrg.com:
University of Wisconsin-Madison researchers have developed a new technique for observing the proteins that operate by that controlling code — called the epigenome — and assembled a library of interactions between the proteins and key positions on packets of DNA.Full article
From PhysOrg.com:
One of the main applications of this research that Cha and her group are interested in is for sensing. "There is no foreseeable route to be able to build a complex array of different nanoscale sensing elements currently," said Cha, a former IBM research scientist who joined the UCSD Jacobs School of Engineering faculty in 2008. "Our work is one of the first clear examples of how you can merge top down lithography with bottom up self assembly to build such an array. That means that you have a substrate that is patterned by conventional lithography, and then you need to take that pattern and merge it with something that can direct the assembly of even smaller objects, such as those having dimensions between 2 and 20 nanometers. You need an intermediate template, which is the DNA origami, which has the ability to bind to something else much smaller and direct their assembly into the desired configuration. This means we can potentially build transistors from carbon nanotubes and also possibly use nanostructures to detect certain proteins in solutions. Scientists have been talking about patterning different sets of proteins on a substrate and now we have the ability to do that."Full article
From PhysOrg.com:
"With these findings, it now should be possible to predict gross features of RNA 3-D shapes based only on their secondary structure, which is far easier to determine than is 3-D structure," Al-Hashimi said. "This will make it possible to gain insights into the 3-D shapes of RNA structures that are too large or complicated to be visualized by experimental techniques such as X-ray crystallography and NMR spectroscopy. The anatomical rules also provide a blueprint for rationally manipulating the structure and thus the activity of RNA, using small molecules in drug design efforts and also for engineering RNA sensors that change structure in user-prescribed ways."Full article
From PhysOrg.com:
A team at The Scripps Research Institute has made major strides in solving a problem that has been plaguing chemists for many years: how best to break carbon-hydrogen bonds and then to create new bonds to join molecules together. This problem is of great interest to the pharmaceutical industry, which currently relies on a method to accomplish this feat that is relatively inefficient and sometimes difficult to perform.Full article
From PhysOrg.com:
A researcher at Iowa State University has discovered how a group of proteins from plant pathogenic bacteria interact with DNA in the plant cell, opening up the possibility for what the scientist calls a "cascade of advances."Full article
From PhysOrg.com:
Although the human genome sequence faithfully lists (almost) every single DNA base of the roughly 3 billion bases that make up a human genome, it doesn't tell biologists much about how its function is regulated. Now, researchers at the Salk Institute provide the first detailed map of the human epigenome, the layer of genetic control beyond the regulation inherent in the sequence of the genes themselves.Full article
From PhysOrg.com:
"Thanks to the Human Genome Project, biology and medicine today may be at a point similar to where physics was after the advent of the telescope," said Orly Alter, assistant professor of biomedical engineering at the university. "The rapidly growing number of large-scale DNA microarray data sets hold the key to the discovery of cellular mechanisms, just as the astronomical tables compiled by Galileo and Tycho after the invention of the telescope enabled accurate predictions of planetary motions and, later, the discovery of universal gravitation. And just as Kepler and Newton made these predictions and discoveries by using mathematical frameworks to describe trends in astronomical data, so future discovery and control in biology and medicine will come from the mathematical modeling of large-scale molecular biological data."Full article
From PhysOrg.com:
A novel technique allows researchers to efficiently and precisely modify or introduce genes into the genomes of human embryonic stem cells (ESCs) and induced pluripotent stem (iPS) cells, according to Whitehead scientists. The method uses proteins called zinc finger nucleases and is described in the August 13 issue of Nature Biotechnology...this method could open a new phase in human genetics.Full article
From PhysOrg.com:
Lawrence Livermore National Laboratory researchers have devised a versatile hybrid platform that uses lipid-coated nanowires to build prototype bionanoelectronic devices.Full article
Mingling biological components in electronic circuits could enhance biosensing and diagnostic tools, advance neural prosthetics such as cochlear implants, and could even increase the efficiency of future computers.
From PhysOrg.com:
Biomolecular computers, made of DNA and other biological molecules, only exist today in a few specialized labs, remote from the regular computer user. Nonetheless, Tom Ran and Shai Kaplan, research students in the lab of Prof. Ehud Shapiro of the Weizmann Institute's Biological Chemistry, and Computer Science and Applied Mathematics Departments have found a way to make these microscopic computing devices 'user friendly,' even while performing complex computations and answering complicated queries.Full article
From PhysOrg.com:
The first known example of a liquid protein has been made by chemists at the University of Bristol opening up the possibility of a number of medical and industrial applications including high-potency pharmaceuticals and protein-based coolants and lubricants.Full article
From PhysOrg.com:
The giant monoliths of Easter Island are worn, but they have endured for centuries. New research suggests that a compound first discovered in the soil of the South Pacific island might help us stand the test of time, too.Full article
